Test method on feline vaccinated with feline...

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G01N 33/53 (2006.01) A61K 39/12 (2006.01) C07K 16/08 (2006.01) C12N 15/00 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2693305

Since FIV-vaccinated cats produce antibodies against FIV, distinguishing them from FIV-infected cats is difficult by serological diagnostic methods using FIV and FIV derived substances. The present invention enables tests for determining the presence or absence of a FIV vaccination history in a cat by detecting antibodies that are produced as a result of vaccination of a cat with an FIV vaccine, but not as a result of FIV infection. Using the methods of the present invention, whether an anti-FIV antibody-positive cat is infected with FIV or has been vaccinated can be conveniently distinguished.

Un félin vacciné par un vaccin contre le VIF produit un anticorps contre un VIF. Par conséquent, dans un sérodiagnostic utilisant un VIF et une substance issue de VIF, il est difficile de distinguer entre un félin qui a été vacciné par un vaccin contre le VIF et un félin qui est infecté par un VIF. Il devient maintenant possible de déterminer la présence ou l'absence de l'historique de vaccination contre le VIF chez un félin par détection d'un anticorps qui est produit par la vaccination par un vaccin contre le VIF mais n'est pas produit par l'infection par un VIF dans le félin. Il est possible de déterminer aisément si ou non un félin positif aux anticorps anti-VIF est infecté par un VIF ou a été vacciné par un vaccin contre le VIF.

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