Diagnostic agents for pancreatic exocrine function

Details Diagnostic agents for pancreatic exocrine function Diagnostic agents for pancreatic exocrine function

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 49/18 (2006.01) A61K 51/00 (2006.01) A61K 51/08 (2006.01) A61K 51/12 (2006.01) C07K 5/04 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2273549

A diagnostic agent for pancreatic exocrine function comprising an amino acid or a peptide containing at least one 13C or 14C atom, or a pharmaceutically acceptable salt thereof other than Bz-Tyr-13C-PABA is provided. A 13C- or 14C-labeled compound represented by the following formula (II): X2-R2-Y2-Z1 ~(II) or a salt thereof, wherein X2 is a hydrogen atom or a protecting group, R2 is a peptide of 2 to 5 amino acids, an amino acid or a single bond, Y2 is an amino acid, Z1 is an amino acid optionally having a protecting group, and at least one of the amino acids in R2, Y2 and Z1, or at least one of the protecting groups in X2 and Z1 when the protecting groups contain a carbon atom, is 13C or 14C-labeled.

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