Method of treating angiogenic tissue growth

Details Method of treating angiogenic tissue growth Method of treating angiogenic tissue growth

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 33/24 (2006.01) A61K 38/18 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2510780

A method of treating a disease or disorder characterized by angiogenic tissue growth is described. The method includes providing an immunoliposome composition comprised of (i) vesicle-forming lipids including between 1-20 mole percent of a vesicle-forming lipid derivatized with a hydrophilic polymer, (ii) a targeting ligand having biological activity to promote angiogenesis, and (iii) a drug entrapped in said liposomes; and administering the immunoliposome composition to a subject.

Cette invention concerne un méthode de traitement d'une maladie ou d'un trouble caractérisé par la croissance de tissu angiogénique. Cette méthodes consiste: à utiliser une composition d'immunoliposomes comprenant (i) des lipides formant des vésicules, dont de 1 à 20 % molaire de lipides formant des vésicules dérivatisés avec un polymère hydrophile, (ii) un ligand de ciblage dont l'activité biologique favorise l'angiogenèse, et (iii) un médicament encapsulé dans lesdits liposomes; et à administre la composition d'immunoliposomes à un sujet.

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