Amylase inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/415 (2006.01) A23J 1/12 (2006.01) A23J 3/18 (2006.01) A23L 1/305 (2006.01) A61K 38/16 (2006.01) C07K 1/36 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2119660

An amylase inhibitor consisting essentially of a protein constructed of 248 amino acid residues having two subunits, each identified as SEQ ID NO:1, in which a single band is observed at a mobility of 0.26 by polyacrylamide gel electrophoresis. The amylase inhibitor is useful as agents for inhibiting an increase in blood glucose level, controlling an insulin secretion and suppressing an appetite, and as food additives. For the same use, the amylase inhibitor is used in combination with a protein composed of two subunits, each identified as SEQ ID NO:2, the total content of both proteins being not less than 20% by weight.

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