C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/711 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/18 (2006.01) C12N 1/21 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2400842
CASB7439 polypeptides and polynucleotides, immunogenic compositions comprising them and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB7439 polypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particularly colorectal cancers, autoimmune diseases, and related conditions.
L'invention concerne des polypeptides et polynucléotides CASB7439, des compositions immunogènes les renfermant et des procédés de préparation de ces polypeptides au moyen de techniques de recombinaison. L'invention concerne également des procédés d'utilisation des polypeptides et polynucléotides CASB7439 dans des diagnostics, ainsi que des vaccins destinés au traitement prophylactique et thérapeutique de cancers, notamment des cancers colorectaux, des maladies auto-immunes et des états pathologiques associés.
Cabezon-Silva Teresa Elisa Virginia
Cassart Jean-Pol
Coche Thierry
Gaulis Swann Roman Jean-Thomas
Vinals Y. de Bassols Carlota
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Smithkline Beecham Biologicals S.a.
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