Process for the resolution of enantiomers of benzopyran...

Details Process for the resolution of enantiomers of benzopyran... Process for the resolution of enantiomers of benzopyran...

C - Chemistry, Metallurgy

07

D

260/373.3

C07D 493/04 (2006.01)

Patent

CA 2029107

Abstract The invention relates to a process for the resolution of enantiomers of 3,4-epoxy-3,4-dihydro-2,2- dimethyl-3-R-2H-1-benzopyran-6-carbonitriles (I), in which R is H or CH3, characterized in that racemic I is dissolved in an inert solvent or solvent mixture together with a small amount of (-)-I [or (+)-I], the solution is seeded with (-)-I [or (+)-I], the precipitated (-)-I [or (+)-I] is isolated, further racemic I is dissolved in the filtrate, seeded with (+)-I [or (-)-I], the precipitated (+)-I [or (-)-I] is isolated and, if desired, this crystallization cycle is repeated one or more times.

Affiliated with

Also associated with

Rating

Process for the resolution of enantiomers of benzopyran... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the resolution of enantiomers of benzopyran..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the resolution of enantiomers of benzopyran... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1357891