Use of an anti-cd151 antibody in the treatment of cancer

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2665912

The present invention relates to the use of at least one antibody, or a functional fragment thereof, capable of binding to the CD151 protein and thus of inhibiting tumour growth, for the preparation of a medicament for use in the treatment of cancer. The invention also relates to a composition for the treatment of cancer, comprising, as active ingredient, at least one anti-CD151 antibody, or a functional fragment thereof, capable of binding to the CD151 protein and/or of inhibiting the development of primary tumours and/or of inhibiting its metastasis-promoting activity, wherein said antibodies may consist of the TS151 and/or TS151r antibodies.

La présente invention a pour objet l'utilisation d'au moins un anticorps, ou l'un de ses fragments fonctionnels, capable de se lier à la protéine CDl 51 et ainsi d'inhiber la croissance tumorale pour la préparation d'un médicament destiné au traitement du cancer. L'invention vise également un composition pour le traitement du cancer, comprenant à titre de principe actif au moins un anticorps anti-CD151, ou l'un de ses fragments fonctionnels, capable de se lier à la protéine CDl 51 et/ou d'inhiber le développement de tumeurs primaires et/ou d'inhiber son activité promotrice de métastase, lesdits anticorps pouvant consister en les anticorps TSl 51 et/ou TS 15 Ir.

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