Silver/water, silver gels and silver-based compositions; and...

A - Human Necessities – 01 – N

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A01N 59/16 (2006.01) A01N 25/04 (2006.01) A01P 1/00 (2006.01) A61K 9/10 (2006.01) A61K 33/38 (2006.01) A61L 2/16 (2006.01) C12N 1/00 (2006.01)

Patent

CA 2624274

We disclose a colorless composition comprising metal particles (e.g., silver nanoparticles) and water, wherein said particles comprise an interior of elemental metal (e.g., silver) and an exterior of metal oxide (e.g., one or more silver oxide(s)), wherein the metal nanoparticles are present in the water at a level of about 5-40 ppm, and wherein the composition manifests significant antimicrobial properties. Methods of use of the composition are described. The composition can be incorporated into a hydrogel with essentially no loss of antimicrobial properties. Various metal-containing compositions with unexpected biological efficacy are also disclosed.

L'invention concerne une composition incolore constituée de particules métalliques (p. ex. des nanoparticules d'argent) et d'eau, lesdites particules comprenant un noyau d'un métal élémentaire (p. ex. argent) et une enveloppe d'un oxyde métallique (p. ex. un ou plusieurs oxyde(s) d'argent). Les nanoparticules métalliques sont présentes dans l'eau selon une teneur de 5-40 mg/l, et la composition manifeste des propriétés antimicrobiennes conséquentes. L'invention concerne des méthodes d'utilisation de la composition. La composition de l'invention peut être incorporée dans un hydrogel sans quasiment aucune dégradation des propriétés antimicrobiennes. L'invention concerne en outre diverses compositions contenant du métal, qui présentent une efficacité biologique inattendue.

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