Novel esters derived from (rr,ss)-2-hydroxybenzoate of...

Details Novel esters derived from (rr,ss)-2-hydroxybenzoate of... Novel esters derived from (rr,ss)-2-hydroxybenzoate of...

C - Chemistry, Metallurgy

07

C

C07C 219/28 (2006.01) A61K 31/24 (2006.01)

Patent

CA 2395976

The invention concerns novel esters derived from (RR,SS)-2-hydroxybenzoate of 3-(2-dimethylaminomethyl-1-hydroxycyclocyclohexyl)phenyl, Tramadol analogs, method for obtaining said esters and to the utilization of said compounds for the production of a medicament having analgesic properties. These novel products of general formula (I) show a higher analgesic activity than tramadol.

L'invention concerne de nouveaux esters dérivés de (RR,SS)-2-hydroxybenzoate de 3-(2-diméthylaminométhyl-1-hydroxycyclohexyl)phényle, analogues au Tramadol, leur procédé de production ainsi que leur utilisation pour la fabrication d'un médicament présentant des propriétés analgésiques. Ces produits, représentés par la formule générale (I), présentent une activité analgésique supérieure à celle du Tramadol.

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