Plaster containing estradiol

Details Plaster containing estradiol Plaster containing estradiol

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2209711

An active substance-containing patch for the controlled release of estradiol or its pharmaceutically acceptable derivatives alone or combined with gestagens, comprising a backing layer, an active substance-containing reservoir which is bonded thereto and pro- duced by using pressure-sensitive adhesives, and a removable protective layer, is characterized by the fact that the pressure- sensitive adhesive comprises ethylcellulose, esters of non-hydro- genated and/or hydrogenated colophony, and lauric acid.

L'invention concerne un emplâtre contenant un principe actif servant à la libération contrôlée d'estradiol ou de ses dérivés tolérables sur le plan pharmaceutique, seuls ou en combinaison avec des gestagènes. Cet emplâtre comprend une couche de fond, un réservoir contenant le principe actif, fixé à ladite couche, produit à l'aide d'adhésifs, ainsi qu'une couche de protection détachable. Cet emplâtre se caractérise en ce que l'adhésif utilisé contient de l'éthylcellulose, des esters de colophane anhydre et/ou hydratée et de l'acide laurique.

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