Reagents for monitoring nuclei acid amplification and...

Details Reagents for monitoring nuclei acid amplification and... Reagents for monitoring nuclei acid amplification and...

C - Chemistry, Metallurgy

07

H

C07H 19/02 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C12Q 1/44 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2482767

Described herein are novel indicator molecules of general formula (I): wherein Q, F ,N, Nuc, X1 and X2 are as defined herein, including their tautomeric forms and their additive salts. The present invention also concerns methods for the use of these molecules to monitor nucleic acid amplificationin real time their applications as diagnostics.

Sont décrites dans cette invention des nouvelles molécules indicatrices représentées par la formule générale (I): dans laquelle Q, F, N, Nuc, X¿1? et X¿2? sont comme définis dans le descriptif, formes tautomères et sels additifs y compris. La présente invention concerne également des méthodes d'utilisation de ces molécules pour la surveillance de l'amplification d'acides nucléiques en temps réel et leurs applications diagnostiques.

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