C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/04 (2006.01) A61K 31/167 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/455 (2006.01) A61K 31/5375 (2006.01) A61P 25/00 (2006.01) C07C 237/48 (2006.01) C07D 213/02 (2006.01) C07D 213/82 (2006.01) C07D 295/04 (2006.01)
Patent
CA 2695071
The present invention relates to the use of a compound of formula (I), wherein R or a pharmaceutically acceptable acid addi-tion salt thereof, for the manufacture of a medicament for the treatment of CNS disorders selected from depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress- related disorders, psychotic disorders such as schizophrenia, neurological dis-eases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic com-plications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeosta-sis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
La présente invention concerne l'utilisation d'un composé de formule (I), dans laquelle R (I) ou un sel d'addition acide acceptable sur le plan pharmaceutique de celui-ci, pour la fabrication d'un médicament pour le traitement de troubles du SNC sélectionnés dans le groupe comprenant dépression, troubles anxieux, troubles bipolaires, troubles déficitaires de l'attention avec hyperactivité (ADHD), troubles liés au stress, troubles psychotiques de type schizophrénie, maladies neurologiques de type maladie de Parkinson, troubles neurodégénératifs de type maladie Alzheimer, épilepsie, migraine, hypertension, abus d'alcool ou d'autres drogues et troubles métaboliques de type troubles alimentaires, diabète, complications diabétiques, obésité, dyslipidémie, troubles de la consommation et de l'assimilation d'énergie, troubles et dysfonctionnement de l'homéostasie de la température corporelle, troubles du sommeil et du rythme circadien, et troubles cardiovasculaires.
Galley Guido
Groebke Zbinden Katrin
Norcross Roger
Stalder Henri
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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