Vector vaccines of bovine herpesvirus 1

Details Vector vaccines of bovine herpesvirus 1 Vector vaccines of bovine herpesvirus 1

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 39/245 (2006.01) A61K 39/295 (2006.01) C07K 14/06 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2136381

The present invention is concerned with a Bovine Herpesvirus I (BHV-I) mutant comprising a heterologous gene introduced into a section of the BHV-I genome. The invention also relates to a vector vaccine comprising such a BHV-I mutant which expresses a heterologous polypeptide derived from a bovine pathogen and induces an adequate immune response in an inoculated host against both FHV an the bovine pathogen. Furthermore, the invention relates to a method for obtaining a BHV-I mutant by self-selection.

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