A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/10 (2006.01) A61K 31/105 (2006.01) A61P 1/16 (2006.01) A61P 9/10 (2006.01) A61P 39/00 (2006.01) C07C 321/00 (2006.01)
Patent
CA 2740568
A method for treating or preventing injury of a biological material exposed to hypoxic or ischemic conditions comprising contacting the biological material with an effective amount of a compound is disclosed. The compound has the following structure (I): R1'-(S)n-R2 or a stereoisomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, and n are as defined herein. Compounds, methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
L'invention porte sur un procédé pour traiter ou prévenir une lésion d'un matériel biologique exposé à des conditions hypoxiques ou ischémiques comprenant la mise en contact du matériel biologique avec une quantité efficace d'un composé. Le composé a la structure suivante (I) : R1_(S)n-R2 ou un stéréoisomère, un sel pharmaceutiquement acceptable ou un promédicament de celui-ci, où R1, R2 et n sont tels que définis ici. L'invention porte également sur des composés, des procédés associés à la préparation et à l'utilisation de tels composés, ainsi que des compositions pharmaceutiques comprenant de tels composés.
Ruan Fuqiang
Wintner Edward Aurel
Ikaria Inc.
Marks & Clerk
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