Immunoassays for anti-hcv antibodies using antigens with...

Details Immunoassays for anti-hcv antibodies using antigens with... Immunoassays for anti-hcv antibodies using antigens with...

G - Physics

01

N

G01N 33/576 (2006.01)

Patent

CA 2139645

Immunoassay methods utilizing HCV envelope antigens that contain conformational epitopes reactive with antibodies in serum from infected individuals are useful for screening and diagnosis. These antigens detect antibodies that are not detected by denaturated HCV envelope antigens. In addition, these HCV envelope antigens comprised of conformational epitopes are more immunologically reactive than a number of other HCV antigens. This is the first evidence that conformational epitopes may be involved in the immunologic response to HCV antigens.

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