Thioether substituted imidazoquinolines

Details Thioether substituted imidazoquinolines Thioether substituted imidazoquinolines

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/437 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2468517

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Des composés d'imidazoquinoléine et de tétrahydroimidazoquinoléine renfermant une fonctionnalité thioéther en position 1 sont utilisés comme modificateurs de réponse immunitaire. Les composés et les compositions de l'invention peuvent induire la biosynthèse de diverses cytokines et sont utilisés dans le traitement d'une variété d'états, y compris les maladies virales et les maladies néoplastiques.

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