C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/74 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2370527
A novel, empirically derived composition of cytokines and myoblasts is described, that allows for the migration of myoblasts through connective barriers, along with methods employing the composition in the in vivo migration of myoblasts for therapeutic purposes and gene therapy, as well as methods for the identification of agents that are agonistic or antagonistic to myoblast migration in vitro or in vivo.
La présente invention concerne une nouvelle composition de cytokines et de myoblastes, obtenue de façon empirique, qui permet la migration des myoblastes à travers des barrières conjonctives. En outre, cette invention concerne des procédés qui utilisent cette composition dans la migration in vivo des myoblastes à des fins thérapeutiques et en thérapie génique, et concerne également des procédés d'identification d'agents agonistes ou antagonistes de la migration de myoblastes in vitro ou in vivo.
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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