Pasteurella haemolytica glycoprotease gene and the purified...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/57 (2006.01) A61K 39/102 (2006.01) A61K 39/40 (2006.01) C07H 21/04 (2006.01) C07K 14/285 (2006.01) C12N 5/06 (2006.01) C12N 9/52 (2006.01) C12Q 1/68 (2006.01) C12S 3/00 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2101781

2101781 9213078 PCTABS00014 A purified DNA molecule comprises a DNA sequence of approximately 975 pb coding for a glycoprotease having a molecular weight of approximately 35.2 kD. The glycoprotease may be isolated from cultures of P.haemolytica. The glycoprotease is specific for cleaving O-glycosylated carbohydrate portions from O-glycoproteins. The glycoprotease has a major cleavage site in glycophorin A between Arg31-Asp32.

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