Potentiation of pharmaceuticals

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/505 (2006.01) A61K 31/135 (2006.01)

Patent

CA 2306233

The present invention provides a method for producing a potentiating effect on a therapeutic action of an agent which is selected from a serotonin re-uptake inhibitor, a norepinephrine re-uptake inhibitors, both a serotonin and norepinephrine re-uptake inhibitor, and an atypical antidepressant in a warm blooded mammal, which comprises administering to said mammal an effective amount of moxonidine, or a pharmaceutically acceptable salt thereof.

La présente invention concerne une méthode permettant de produire un effet potentialisateur sur l'action thérapeutique d'un agent sélectionné parmi un inhibiteur du recaptage de la sérotonine, des inhibiteurs du recaptage de la noradrénaline, un inhibiteur du recaptage de la sérotonine et de la noradrénaline, et un antidépresseur atypique, chez un mammifère à sang chaud. Cette méthode consiste à administrer audit mammifère une dose efficace de moxonidine ou d'un de ses sels acceptables pharmaceutiquement.

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