Nitrogen-containing fused heterocyclic carboxylic acid...

Details Nitrogen-containing fused heterocyclic carboxylic acid... Nitrogen-containing fused heterocyclic carboxylic acid...

C - Chemistry, Metallurgy

07

D

C07D 491/20 (2006.01) C07D 491/147 (2006.01)

Patent

CA 2533685

The present invention is directed to a nitrogen-containing fused heterocyclic carboxylic acid having an absolute configuration of "R" of the formula [XIX]: Image wherein Y is a member selected from the group consisting of a phenylsulfonyl, naphthylsulfonyl and biphenylylsulfonyl group which may be unsubstituted or substituted by a member selected from a nitro group, a C1-6 alkyl group, a C1-6 alkoxy group, a C3-6 cycloalkyl group, a halogen atom, and a thienyl group or C1-6 alkylsulfonyl group, and n is 0 or 1, or a salt thereof. The compounds of the present invention are used as intermediates in processes for the preparation of camptothecin derivatives having antitumor activities.

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