Gamma secretase modulators

Details Gamma secretase modulators Gamma secretase modulators

C - Chemistry, Metallurgy

07

D

C07D 233/60 (2006.01) A61K 31/4164 (2006.01) A61P 25/28 (2006.01) C07D 417/10 (2006.01) C07D 419/10 (2006.01)

Patent

CA 2695864

This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Compounds of formula (I) include compounds of formulas (IA) and (IB). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).

L'invention concerne de nouveaux composés qui sont des modulateurs de gamma secrétase. Les composés sont de formule (I). Les composés de la formule (I) comprennent des composés de formules (IA) et (IB). Des procédés de modulation de l'activité de gamma secrétase et des procédés de traitement de la maladie d'Alzheimer utilisant les composés de la formule (I) sont également décrits.

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