C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/50 (2006.01) C07K 14/705 (2006.01) C07K 16/44 (2006.01) C12N 5/18 (2006.01) C12N 9/00 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2007818
ABSTRACT A catalytic molecule comprising a receptor molecule containing an antibody combining site that immunologically binds to a plurality of polyvalent metal ion-containing coordination complexes is disclosed. The coordination complex of a first immunoligand is kinetically inert, whereas the coordination complex of a second immunoligand is kinetically labile. The receptor molecule catalyzes a reaction of the second immunoligand. Immunogens, antigens, and methods of making and using the catalytic receptors are disclosed, as are receptor molecules that catalyze the hydrolysis of a predetermined peptide bond.
Iverson Brent L.
Lerner Richard A.
Fetherstonhaugh & Co.
Scripps Clinic And Research Foundation
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