Aids therapy and vaccine

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/70 (2006.01) A61K 39/21 (2006.01) A61K 39/42 (2006.01) C07K 7/08 (2006.01) C07K 14/16 (2006.01) C07K 14/725 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) F02B 75/02 (2006.01)

Patent

CA 2069507

The present invention provides therapy and prophylaxis against HIV-induced AIDS, as well as methods for ascertaining the susceptibility of an individual to HIV-induced AIDS, the invention being based on the discovery that AIDS results from gp120 of HIV mimicking the antigen-presenting component of the immune system, thereby spuriously activating certain + T cells in susceptible individuals, leading to a condition similar to graft versus host disease, the condition being treatable by eliminating the responsible T cells, for example.

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