Red blood cell storage solution

Details Red blood cell storage solution Red blood cell storage solution

A - Human Necessities

01

N

A01N 1/02 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2071833

The present invention provides an improved aqueous solution for suspending and storing red blood cells. The solution includes sodium citrate, a combination of sodium biphosphate and sodium phosphate dibasic, adenine, and mannitol. The solution is formulated at a low osmolarity and has a physiological pH of approximately 7.4. The solution simultaneously maintains stored red cells ATP and 2,3-BPG.

La présente invention consiste en une solution aqueuse améliorée pour la mise en suspension et la conservation des érythrocytes. La solution en question contient du citrate de sodium, une combinaison de diphosphate de sodium et de phosphate de sodium dibasique, de l'adénine et du mannitol. La solution est formulée à faible osmolarité et présente un pH physiologique d'environ 7,4. La solution maintient simultanément des érythrocytes ATP et 2,3-BPG conservés.

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