Composition and method for reducing recovery time in...

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01) A61K 31/00 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/225 (2006.01) A61K 31/66 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2239421

A method of reducing the recovery time from anaesthesia in aged mammals, the method comprising treating the mammal with a non-toxic, enhancing effective amount of a cell membrane permeant calcium buffer. The buffer is preferably a calcium ion chelating agent having a K D selected from the range 1 × 10 -4 to 1 × 10 -8 Molar and being essentially calcium ion-selective over other metal ions. A most preferred buffer is BAPTA-AM.

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