Production of novel polypeptide

C - Chemistry – Metallurgy – 12 – N

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195/1.2, 195/1.2

C12N 15/63 (2006.01) C07K 14/47 (2006.01) C12N 1/00 (2006.01) C12N 15/11 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2010593

TITLE: PRODUCTION OF NOVEL POLYPEPTIDE ABSTRACT Disclosed are (1) a DNA containing a DNA segment coding for a polypeptide having EAQ as the N-terminal sequence and composed of 60 amino acids, (2) a recombinant DNA constructed by introducing the DNA sequence in an expression vector for Escherichia coli , yeast or animal cells so as to express the foregoing polypeptide, (3) a transformant bearing the recombinant DNA and (4) a process for producing the foregoing polypeptide comprising cultivating the transformant, accumulating the polypeptide and collecting the same, whereby the polypeptide can be obtained in large amounts and is useful for the elucidation of the growth mechanism of cancer cells and the development of the therapeutic agents for carcinoma.

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