Heterologous antigens in live cell vaccine strains

Details Heterologous antigens in live cell vaccine strains Heterologous antigens in live cell vaccine strains

A - Human Necessities

61

K

A61K 39/116 (2006.01) A61K 39/106 (2006.01) A61K 39/295 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 37/04 (2006.01) C07K 14/245 (2006.01) C07K 14/25 (2006.01) C07K 14/28 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2156191

A bacterial cell (preferably a gram-negative, enteric bacterium such as V. cholerae) the chromosome of which contains a DNA sequence encoding a heterologous antigen, which sequence is functionally linked to an iron-regulated promoter such as the irgA promoter of V. cholerae.

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