Use of pyrazolo [1 , 5 -a] pyrimidine derivatives for...

Details Use of pyrazolo [1 , 5 -a] pyrimidine derivatives for... Use of pyrazolo [1 , 5 -a] pyrimidine derivatives for...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61P 9/00 (2006.01) A61P 19/00 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2627623

The present invention provides methods for inhibiting protein kinases selected from the group consisting of AKT, Checkpoint kinase, Aurora kinase, Pirn kinases, and tyrosine kinase using pyrazolo[1 ,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with protein kinases using such compounds.

La présente invention concerne des méthodes destinées à inhiber des protéines kinases choisies dans le groupe constitué par l'AKT, la kinase point de contrôle, la kinase Aurora, les kinases Pim et la tyrosine kinase au moyen de composés pyrazolo[1,5-a]pyrimidine, ainsi que des méthodes destinées à traiter, prévenir, inhiber ou atténuer une ou plusieurs maladies associées aux protéines kinases au moyen de ces composés.

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