Carboxamide derivatives and the use thereof as factor xa...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61K 31/4965 (2006.01) A61K 31/5375 (2006.01) A61P 7/00 (2006.01) A61P 9/00 (2006.01) C07D 241/18 (2006.01) C07D 265/06 (2006.01) C07D 265/10 (2006.01) C07D 265/32 (2006.01) C07F 9/09 (2006.01)

Patent

CA 2514100

The invention relates to the novel compounds of formula (I), wherein R1, D, X, W, Y and T are defined as in claim 1, for example (II). The novel compounds inhibit coagulation factor Xa and can be used for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.

L'invention concerne les composés représentés par la formule (I) dans laquelle R?1¿, D, X, W, Y et T ont la signification donnée dans la revendication (1), par ex. (II). Lesdits composés sont des inhibiteurs du facteur de coagulation Xa et peuvent être employés dans la prophylaxie et/ou la thérapie de maladies thrombo-emboliques, et le traitement de tumeurs.

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