C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/207, 260/250
C07C 327/44 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07D 207/337 (2006.01) C07D 213/57 (2006.01) C07D 213/59 (2006.01) C07D 233/61 (2006.01) C07D 235/16 (2006.01) C07D 277/64 (2006.01) C07D 333/24 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2037483
Abstract of the Disclosure: There is disclosed a thiocarbamoylacetonitrile compound represented by the formula: Image ( I ) wherein R1 represents hydrogen, a C1 to C6 alkyl, a C3 to C6 cycloalkyl or -(CH2)n-A (where A represents a C6 to C12 aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group constituted by 9 or 10 atoms, each of which may be substituted by at least one selected from a C1 to C6 alkyl and a halogen, and n is O or an integer of 1 to 6), R2 represents a Cl to C10 alkyl, and Ar represents an aryl, a 5- or 6-mem- bered heterocyclic group or a fused heterocyclic group, each of which may be substituted by at least one substituent selected from the group consisting of a C1 to C6 alkyl, a C1 to C6 alkoxy, a C2 to C7 alkyl- carbonyl, a C7 to C13 arylcarbonyl, a C1 to C6 alkyl- amino, a C2 to C6 dialkylamino, amino, formylamino, a C2 to C7 alkylcarbonylamino, a halogen, cyano, nitro, hydroxyl, a C1 to C6 alkylthio, a C6 to C12 arylthio, a C1 to C6 alkylsulfinyl, a C6 to C12 arylsulfinyl, a C1 to C6 alkylsulfonyl, a C6 to C12 arylsulfonyl, aminosulfonyl, a C1 to C6 alkylaminosulfonyl, a C2 to C6 dialkylaminosulfonyl, trifluoromethyl and imida- zolyl.
Bessho Hideki
Hayashi Junko
Kobayashi Makio
Okushima Hiromi
Seino Asami
Mitsubishi Chemical Corporation
Smart & Biggar
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