Single nucleotide polymorphisms in mitochondrial genes that...

Details Single nucleotide polymorphisms in mitochondrial genes that... Single nucleotide polymorphisms in mitochondrial genes that...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2370884

Compositions and methods based on determination of single nucleotide polymorphisms in mtDNA or homoplasmic mtDNA mutations are provided that are useful for detecting the presence of or risk for having Alzheimer's disease (AD), and for identifying agents suitable for treating AD.

La présente invention porte sur des compositions et des méthodes fondées sur la détermination de polymorphismes de nucléotides simples dans l'ADN mt ou dans des mutations homoplasmiques d'ADN mt, utilisées pour détecter la présence de la maladie d'Alzheimer (AD) ou le risque de l'avoir, et pour identifier des agents appropriés pour traiter cette maladie.

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