Thyrotropin-releasing hormone analogs and method of use

Details Thyrotropin-releasing hormone analogs and method of use Thyrotropin-releasing hormone analogs and method of use

A - Human Necessities

61

K

A61K 38/05 (2006.01) A61K 38/00 (2006.01) A61K 38/02 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 2/00 (2006.01) C07K 5/06 (2006.01) C07K 5/10 (2006.01) C07K 7/04 (2006.01)

Patent

CA 2605122

The invention provides a method of modulating blood glucose levels by treating or preventing pancreas-related disorders with thyrotropin-releasing hormone (TRH) or a TRH derivative. Diabetes mellitus, pancreatic islet destruction, pancreatic beta cell malfunction, and hyperglycemia-related malfunction are preferably treated or prevented.

L'invention concerne une méthode permettant de moduler les taux de glucose sanguin, consistant à traiter ou à prévenir les troubles d'origine pancréatique au moyen de l'hormone de libération de la thyrotropine (TRH) ou d'un dérivé de TRH. Les affections traitées comprennent de préférence le diabète sucré, la destruction des îlots pancréatiques, les dysfonctions des cellules bêta pancréatiques, et les dysfonctions associées à l'hyperglycémie.

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