Therapeutical composition containing dendritic cells and use...

Details Therapeutical composition containing dendritic cells and use... Therapeutical composition containing dendritic cells and use...

A - Human Necessities

61

K

A61K 35/14 (2006.01) A61K 35/26 (2006.01) A61K 35/66 (2006.01) A61K 38/21 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2524910

The present invention relates to a method for the preparation of a therapeutical composition, in particular, the present invention relates to a method for treating dendritic cells with a combination of at least one interferon gamma receptor agonist and at least one toll like receptor 2 and/or TLR 6 agonist and using these pretreated dendritic cells for the preparation of a therapeutical composition. Moreover, the present invention relates to a therapeutical composition containing dendritic cells and the use thereof for the treatment of various diseases and disorders.

L'invention concerne un procédé de préparation d'une composition thérapeutique, notamment un procédé de traitement de cellules dendritiques à l'aide d'une combinaison d'au moins un agoniste du récepteur de l'interféron gamma et d'au moins un récepteur 2 de type Toll et/ou l'agoniste TLR 6, et l'utilisation de ces cellules dendritiques pré-traitées pour la préparation d'une composition thérapeutique. Par ailleurs, l'invention porte sur une composition thérapeutique contenant des cellules dendritiques et son utilisation pour le traitement de maladies et troubles divers.

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