Compounds and uses thereof-848

C - Chemistry – Metallurgy – 07 – D

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C07D 471/14 (2006.01) A61K 31/4745 (2006.01)

Patent

CA 2691237

This invention relates to novel compounds having the structural formula (I) below: and their pharmaceutically acceptable salts, tautomers or in vivo-hydrolysable precursors, compositions and methods of use thereof, wherein R1, R2, R3, R4 R5, and R6 are defined in the specification. These novel compounds provide a treatment or prophylaxis of anxiety disorders, schizophrenia, cognitive disorders, and/or mood disorders.

Cette invention porte sur de nouveaux composés présentant la formule structurale (I) ci-après : et sur leurs sels, tautomères ou précurseurs hydrolysable in-vivo, pharmaceutiquement acceptables, et sur des compositions et des procédés pour leur utilisation. Dans la formule (I), R1, R2, R3, R4, R5, et R6 sont définis dans la description. Ces nouveaux composés fournissent un traitement ou une prophylaxie de troubles de l'anxiété, de la schizophrénie, de troubles cognitifs et/ou de troubles de l'humeur.

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