Treating red blood cell solutions with anti-viral agents

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/06 (2006.01) A01N 43/00 (2006.01) A61K 35/14 (2006.01) A61L 2/00 (2006.01) A61L 2/18 (2006.01) C07D 219/12 (2006.01) C07D 311/94 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2203885

Methods and compositions for treating pathogens in material are described, including methods of decontaminating human fluids prior to processing in the clinical laboratory and methods for decontaminating blood products prior to in vivo use. The techniques handle large volumes of human serum without imparing the testing results. Novel compounds for photodecontaminating biological material are also contemplated which are compatible with clinical testing, in that they do not interfere with serum analytes.

L'invention concerne des procédés et des compositions pour traiter des agents pathogènes dans un matériau biologique, et notamment des procédés pour décontaminer des fluides humains avant leur traitement en laboratoire clinique, et des procédés pour décontaminer des produits sanguins avant leur emploi in vivo. Ces techniques permettent de manipuler d'importants volumes de sérum humain sans altérer les résultats d'analyse. L'invention décrit par ailleurs de nouveaux composés pour photodécontaminer un matériau biologique, qui sont compatibles avec l'expérimentation clinique, en ce sens qu'ils n'interfèrent pas avec les analytes sériques.

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