Process for the preparation of optically active...

Details Process for the preparation of optically active... Process for the preparation of optically active...

C - Chemistry, Metallurgy

07

D

C07D 215/18 (2006.01)

Patent

CA 2680610

Optically active ethenylphenyl-alcohols of formula (I) or its mirror image, wherein R1 is unsubstituted or substituted heteroaryl and R2 is phenyl or substituted aryl, are prepared by asymmetric hydrogenation of the corresponding ketones applying hydrogen gas in the presence of specific platinum metal complex catalysts.

Alcools éthénylphényliques optiquement actifs de formule (I) ou leur image miroir, où R1 représente hétéroaryle non substitué ou substitué, et R2 représente phényle ou aryle substitué, préparés par hydrogénation asymétrique des cétones correspondantes en appliquant de l'hydrogène gazeux en présence de catalyseurs spécifiques de complexes métalliques de platine.

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