Production process for antibody composition

Details Production process for antibody composition Production process for antibody composition

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/395 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 31/14 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 37/04 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2481837

A process for producing an antibody composition with the use of cells characterized by using cells tolerant to a lectin recognizing a sugar chain structure in which an .alpha.-bond is formed between the 6-position of N- acetylglucosamine at the reducing end of an N-glycoside bond-type complex sugar chain and the 1-position of fucose; and cell usable in this process.

Cette invention a trait à un procédé de production d'une composition anticorps préparée avec des cellules tolérantes à la lectine, reconnaissant une structure de chaîne de sucre dans laquelle est formée une liaison-.alpha. entre la position 6 de N-acétyglucosamine à l'extrémité de réduction d'une chaîne de sucre complexe du type à liaison N-glycoside et la position 1 de fucose. Elle porte également sur des cellules pouvant être utilisées avec ce procédé.

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