Pharmaceutical formulation containing an hmg-coa reductase...

A - Human Necessities – 61 – K

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A61K 9/20 (2006.01) A61K 31/40 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2621134

The present invention relates to improved pharmaceutical formulation for oral administration comprising a therapeutically effective quantity of an HMG-CoA reductase inhibitor, and more particularly Fluvastatin, Atorvastatin or salts thereof in combination with a linear sulphated polysaccharide such as Carrageenan and a method for the preparation thereof.

La présente invention concerne une formulation pharmaceutique améliorée pour administration orale, ladite formulation pharmaceutique comprenant une quantité thérapeutiquement efficace d'un inhibiteur de la HMG-CoA réductase, et plus particulièrement la fluvastatine, l'atorvastatine ou leurs sels, en combinaison avec un polysaccharide sulfaté linéaire tel que la carragénine. L'invention concerne également un procédé de préparation de ladite formulation pharmaceutique.

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