3- (aminomethyliden) 2-indolinone derivatives and their use...

Details 3- (aminomethyliden) 2-indolinone derivatives and their use... 3- (aminomethyliden) 2-indolinone derivatives and their use...

C - Chemistry, Metallurgy

07

D

C07D 209/34 (2006.01) A61K 31/404 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/12 (2006.01) C07D 487/10 (2006.01) C07D 491/08 (2006.01)

Patent

CA 2646638

The present invention encompasses compounds of general formula (1) wherein R1, R2, R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.

La présente invention comprend des composés de formule générale (1), dans laquelle R1, R2, R3 et X sont tels que définis dans la revendication 1, qui sont appropriés pour le traitement des maladies caractérisées par une prolifération cellulaire excessive ou anormale, et leur utilisation pour préparer une composition pharmaceutique présentant les propriétés mentionnées ci-dessus.

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