Non-human primate fc receptors and methods of use

Details Non-human primate fc receptors and methods of use Non-human primate fc receptors and methods of use

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) C07K 14/735 (2006.01) C07K 16/32 (2006.01) C07K 16/42 (2006.01) C07K 19/00 (2006.01) C12N 15/10 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2466885

The invention provides isolated non-human primate Fc receptor polypeptides, the nucleic acid molecules encoding the Fc receptor polypeptides, and the processes for production of recombinant forms of the Fc receptor polypeptides, including fusions, variants, and derivatives thereof. The invention also provides methods for evaluating the safety, efficacy and biological properties of Fc region containing molecules using the non-human primate Fc receptor polypeptides.

L'invention concerne des polypeptides formant des récepteurs Fc de primates non humains, des molécules d'acide nucléique codant pour lesdits polypeptides, et des procédés servant à la production de formes recombinées desdits polypeptides, notamment leurs protéines hybrides, leurs variants, et leurs dérivés. L'invention concerne également des procédés d'évaluation de la sûreté, de l'efficacité, et des propriétés biologiques des molécules contenant des régions Fc au moyen des polypeptides formant des récepteurs Fc de primates non humains.

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