Self-adjuvanting peptide vaccine delivery system and...

Details Self-adjuvanting peptide vaccine delivery system and... Self-adjuvanting peptide vaccine delivery system and...

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2114125

2114125 9302706 PCTABS00019 The present invention provides self-adjuvanting vaccines for use in raising antibodies to peptides without the use of oil or alum adjuvants. Further, the present invention provides methods of therapy using these vaccines and has particular application in chemical castration. In one aspect the vaccine comprises in admixture a peptide conjugated to 1-3 fatty acids and a peptide conjugated to a carrier protein. In preferred forms the peptide is conjugated to the fatty acids via a tromethamine or ethanolamine derivative. The preferred protein carrier is Type 4 fimbriae.

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