Somatostatin-dopamine chimeric analogs

Details Somatostatin-dopamine chimeric analogs Somatostatin-dopamine chimeric analogs

C - Chemistry, Metallurgy

07

K

C07K 7/00 (2006.01) C07D 471/04 (2006.01) C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2449634

Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo. An example is : 6-n-propyl- 8.beta.-ergolinglmethylthioacetyl-D-Phe-c-(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH2

La présente invention concerne une série d'analogues chimériques de somatostatine-dopamine qui retient l'activité de la somatostatine et de la dopamine in vivo. C'est le cas par exemple du : 6-n-propyle-8.beta.-ergolinglméthylthioacétyle-D-Phe-c-(Cys-Tyr-D-Trp-Lys-Abu-Cys)-Thr-NH¿2?.

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