Cobalamin taxane bioconjugates for treating eye disease

A - Human Necessities – 61 – K

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Details

A61K 31/714 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2750649

The present invention is directed to methods of treating eye disease. In one embodiment, the method can comprise administering a bioconjugate to a subject to treat the eye disease, where the bioconjugate comprises a taxane covalently bonded to a cobalamin. Additionally, the bioconjugate can be dissolved in an aqueous solution prior to administration.

La présente invention porte sur un procédé de traitement d'une maladie oculaire. Dans un mode de réalisation, le procédé peut comprendre l'administration d'un bioconjugué à un sujet dans le but de traiter la maladie oculaire, le bioconjugué comprenant un taxane lié de manière covalente à une cobalamine. De plus, le bioconjugué peut être dissous dans une solution aqueuse avant l'administration.

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