Oxazolidines as 5-ht2a-antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/14 (2006.01) A61K 31/445 (2006.01) C07D 491/056 (2006.01)

Patent

CA 2281918

The invention relates to novel oxazolidine derivatives of formula (I), wherein R1, R2 and R3 have the meaning cited in Claim 1. The invention further relates to the salts thereof and to a method for the production of the inventive compounds. The compounds of formula (I) act as 5-HT2A antagonists having a reuptake-inhibiting, antidepressant or anxiolytic effect and can be used in the production of medicaments.

L'invention concerne de nouveaux dérivés d'oxazolidine de la formule (I) dans laquelle R<1>, R<2> et R<3> ont les significations mentionnées dans la revendication 1. L'invention concerne également leurs sels et un procédé permettant de préparer ces composés. Les composés de la formule (I) agissent comme 5-HT2A-antagonistes ayant une action inhibitrice de la réabsorption, antidépressive ou anxiolytique et s'utilisent pour préparer des médicaments.

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