Agglutination assay

Details Agglutination assay Agglutination assay

G - Physics

01

N

G01N 33/58 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/548 (2006.01) G01N 33/558 (2006.01)

Patent

CA 2629290

The invention relates to agglutination assays and related kits, reagents and devices. In particular methods of assaying small analytes having few epitopes are disclosed, by means of using hub moieties to which multiple analytes may be bound by a first epitope, together with a further moiety capable of binding a second analyte epitope and which is also capable of binding to a detectable particle. Stable agglutinated complexes may be so formed, which may used as the basis for various assay formats.

La présente invention concerne des analyses par agglutination ainsi que les kits, réactifs et dispositifs associés. La présente invention concerne en particulier des procédés pour l~analyse de petits échantillons ayant peu d~épitopes, grâce à des groupes fonctionnels auxquels de multiples parties de l~échantillon à analyser peuvent se lier par un premier épitope, ainsi qu~à un autre groupe fonctionnel pouvant se lier à un second épitope à analyser et pouvant se lier à une particule détachable. Des complexes agglutinés stables peuvent ainsi se former et servir de base à divers formats d~analyses.

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