Piezoelectric cell growth biosensing method and system

Details Piezoelectric cell growth biosensing method and system Piezoelectric cell growth biosensing method and system

C - Chemistry, Metallurgy

12

Q

C12Q 1/04 (2006.01) C12M 1/34 (2006.01) G01N 33/543 (2006.01) H01L 41/08 (2006.01)

Patent

CA 2064188

2064188 9101381 PCTABS00003 The invention relates to a piezoelectric biosensor device and also to a method and a system utilizing a piezoelectric biosensor device for detecting metabolic growth requirements, antibiotic responses, and the specific bacterial products of microorganisms. When a microorganism is grown in an appropriate nutrient medium containing a metabolite-responsive polymer, metabolic products of the organism acidify the medium and precipitate a polymer/metabolite complex which desposits or accumulates on the surface of a piezoelectric biosensor device. The mass change on the surface of the device resulting from this deposit produces a change in the resonant frequency of the piezoelectric biosensor device which can be used to determine the growth and type of microorganism.

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