Methods for isolating crystalline form i of 5-azacytidine

C - Chemistry – Metallurgy – 07 – D

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C07D 251/10 (2006.01)

Patent

CA 2518973

The invention includes methods for isolating crystalline Form I of 5- azacytidine substantially free of other forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising Form I of 5-azacytidine.

L'invention se rapporte à des procédés permettant d'isoler la forme I cristalline de la 5-azacytidine, en excluant sensiblement toute autre forme, la 5-azacytidine étant représentée par la formule (I). L'invention se rapporte également à des compositions pharmaceutiques comportant la forme I de la 5-azacytidine.

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