Gastroresistant pharmaceutical dosage form comprising...

A - Human Necessities – 61 – K

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Details

A61K 9/26 (2006.01) A61K 9/58 (2006.01) A61K 31/403 (2006.01)

Patent

CA 2559685

The present invention relates to the pharmaceutical dosage forms which enable a controlled and/or a targeted delivery of an active substance to the selected regions of gastrointestinal tract of humans or animals. The pharmaceutical dosage forms preferably comprises the active substance N-(2~(2- phthalimidoethoxy)-acetyl)-L-alanyl-D-glutamic acid (designated as LK 423). Methods of treatment of chronic inflammatory diseases of gastrointestinal tract of humans and / or animals by using the pharmaceutical dosage forms of the invention are disclosed.

Cette invention se rapporte à des formes galéniques pharmaceutiques qui permettent une administration régulée et/ou ciblée d'une substance active dans les zones sélectionnées du tractus gastro-intestinal chez l'homme ou chez les animaux. Ces formes galéniques pharmaceutiques contiennent de préférence la substance active acide N-(2-(2-phtalimidoéthoxy)-acétyl)-L-alanyl-D-glutamique (appelée LK 423). Cette invention concerne également des procédés pour traiter les maladies inflammatoires chroniques du tractus gastro-intestinal chez l'homme et/ou chez les animaux en utilisant ces formes galéniques pharmaceutiques.

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