Novel thiophene derivatives as sphingosine-1-phosphate-1...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 413/04 (2006.01) A61K 31/4245 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2602475

The invention relates to novel thiophene derivatives of formula (l),their preparation and their use as pharmaceutically active compounds. Said compounds particulary act as immunosuppressive agents. wherein ring A represents oxadiazole and the other substituents are as defined in the description.

L'invention concerne de nouveaux dérivés de thiophène représentés par la formule (I), leur préparation et leur utilisation sous forme de composés actifs sur le plan pharmaceutique. Ces composés servent en particulier d'agents immunosuppresseurs. Dans la formule, le noyau A représente oxadiazole et les autres substituants sont tels qu'ils sont définis dans le descriptif.

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