A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/352 (2006.01) A61K 31/335 (2006.01) A61K 31/35 (2006.01)
Patent
CA 2419741
The present invention provides an anti-constipation composition containing a halogenated-bi-cyclic 15-keto prostaglandin derivative as an active ingredient in a ratio of bi-cyclic/mono-cyclic structure of at least 1:1. The halogenated-bi-cyclic 15-keto prostaglandin derivative is represented by Formula (I): (see formula I) where X1 and X2 are preferably both fluorine atoms. The composition can be used to treat constipation without substantive side-effects, such as stomachache.
L'invention concerne une composition contre la constipation contenant un composé halogéné bicyclique en tant qu'ingrédient actif dans une rapport de structure bicyclique/monocyclique d'au moins 1: 1. Ce composé halogéné bicyclique est représenté par la formule (I), dans laquelle X1 et X2 sont de préférence tous deux des atomes de fluor. Cette composition peut être utilisée pour soigner la constipation sans provoquer des effets secondaires importants, tels qu'une gastralgie.
Ueno Ryuji
Kirby Eades Gale Baker
Sucampo Ag
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